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Title: Evaluation of in vivo pathogenicity of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis with different enzymatic profiles in a murine model of disseminated candidiasis
Authors: Treviño Rangel, Rogelio
Rodríguez Sánchez, Iram Pablo
Elizando Zertuche
Martínez Fierro, Margarita de la Luz
Garza Veloz, Idalia
Romero Diaz, Viktor
González, Jose
González, Gloria
Issue Date: Feb-2014
Publisher: International Society for Human and Animal Mycology
Oxford Academic
Abstract: Six isolates of the Candida parapsilosis complex with different enzymatic profiles were used to induce systemic infection in immunocompetent BALB/c mice. Fungal tissue burden was determined on days 2, 5, 10, and 15 post challenge. The highest fungal load irrespective of post-infection day was detected in the kidney, followed by the spleen, lung,andliver,withatendencyforthefungalburdentodecreasebyday15inallgroups. Significant differences among the strains were not detected, suggesting that the three species of the “psilosis” group possess a similar pathogenic potential in disseminated candidiasis regardless of their enzymatic profiles
ISSN: 1365-280X
Other Identifiers: info:eu-repo/semantics/publishedVersion
Appears in Collections:*Documentos Académicos*-- Doc. en Ing. y Tec. Aplicada

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