Treviño Rangel, Rogelio; Rodríguez Sánchez, Iram Pablo; Elizando Zertuche; Martínez Fierro, Margarita de la Luz; Garza Veloz, Idalia; Romero Diaz, Viktor; González, Jose; González, Gloria
Resumen:
Six isolates of the Candida parapsilosis complex with different enzymatic profiles were used to induce systemic infection in immunocompetent BALB/c mice. Fungal tissue burden was determined on days 2, 5, 10, and 15 post challenge. The highest fungal load irrespective of post-infection day was detected in the kidney, followed by the spleen, lung,andliver,withatendencyforthefungalburdentodecreasebyday15inallgroups. Significant differences among the strains were not detected, suggesting that the three species of the “psilosis” group possess a similar pathogenic potential in disseminated candidiasis regardless of their enzymatic profiles